Senior Associate Scientist, Oncology Drug Discovery / Biology-6818140826
Description
Janssen Research & Development, L.L.C., a Johnson & Johnson company, is recruiting for a Senior Associate Scientist, Oncology Drug Discovery / Biology to be located in Spring House, PA.
Janssen Research & Development, L.L.C. is a fully integrated biopharmaceutical and biotechnology company. As a world leader in the field of biomedicines, Janssen strives to develop innovative treatments to improve the health of people worldwide. At the forefront of monoclonal antibody technology and manufacturing, Janssen Research & Development manufactures products including REMICADE® (infliximab), STELARA™ (ustekinumab) and SIMPONI™ (golimumab) for the treatment of various immunological diseases.
Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion. Proud to be an equal opportunity employer.
The Senior Associate Scientist will join the Hematologic Malignancies Disease Area Stronghold and focus research efforts in the discovery and development of biologics that directly impact tumor growth or function as immune modulators for the treatment of cancer. S/he will be responsible for independently contributing to and possibly leading one of the research programs across the different stages of pre-clinical drug discovery. His/her responsibilities include the design, execution and interpretation of studies for the validation and characterization of new targets and therapeutic agents in the area of hematologic malignancies and tumor immunology. The scientist will effectively and frequently collaborate with colleagues in the oncology, immunology and antibody development groups as well as present scientific results to their research group and multidisciplinary teams.
The Senior Associate Scientist will join one or more ongoing programs, and may eventually initiate a novel large molecule drug discovery program in hematologic malignancy and/or tumor immunology. The successful candidate will: Demonstrate ability to design, perform and interpret complex in vitro, ex vivo and in vivo experiments; Develop expertise in flow cytometry, and may obtain advanced training in multicolor flow cytometry; Demonstrate the ability to analyze and present data in professional 'publication ready' format; Demonstrate the ability to work independently and manage multiple experiments simultaneously; Demonstrate the ability to contribute to various projects outside of his/her own, and collaborate with stakeholders from all relevant functions; Keep up-to-date with the literature related to his/her field; Demonstrate clear and professional verbal and written communication.
Qualifications
MS with at least 6 years of experience OR a BS/BA degree with at least 9 years of experience, performing progressively advanced duties at the Associate Scientist II level or equivalent is required
Must be proficient in cell biology assays that could include FACS, ELISAs, cell proliferation, cellular cytotoxicity, immune cell isolation from whole blood or tissues, cell culture, transfection and cloning of stable cell lines, ADCC, CDC
Previous experience with IC50 determination, MSD, electrophoresis, and microscopy are preferred
The successful candidate will be intellectually curious and well informed on the latest scientific advances in the field, and will demonstrate creativity and novel approaches to solving scientific problem
Experience in preclinical drug discovery or validation of drug targets is preferred
Strong cell biology and assay skills are required
Experience with tumor cells (solid tumor or hematologic cancer) is preferred
Previous experience in flow cytometry is preferred
Experience with analysis of immune cell function or characterization in is preferred
Familiarity with tumor models and mechanisms of anti-tumor responses with strength in the analysis of the activity of T cells, macrophages and NK cells in anti-tumor immunity is preferred
Demonstrated ability to work independently and manage multiple experiments simultaneously is required
Excellent interpersonal skills with the ability to interact effectively with people, internally and externally is required
Detail-oriented, with excellent record-keeping skills is required
Excellent oral and written communication skills are required
Able to effectively present scientific data and concepts to international standards is required
This position is located in Spring House, PA.
There will be up to 10% travel.
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J2W:BIO
J2W:NSJ
J2W:MZ
Primary Location:North America-United States-Pennsylvania-Spring House
Organization: Janssen Research & Development, LLC. (6084)
Job Function: R&D
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