Senior Scientist Viral Vaccines-00000PL3
Description
Crucell is a global biotech company that focuses on the development, production and marketing of vaccines and antibodies to prevent and combat infectious diseases.
Within Crucell talented, entrepreneurial people are working in a dynamic culture in which innovation and a ‘can do’ state of mind are the central points. In order to strengthen our team we are continuously looking for enthusiastic, talented people who have the ambition to develop themselves and can be of value to Crucell.
For our Pre-clinical characterization department, we are looking for a
Senior Scientist Viral Vaccines (m/f)
Department/Project:
The Viral Vaccine department is part of the discovery and early development laboratory and focuses on the research and development of vaccines against viral infectious diseases. Within the Viral Vaccine department, the Preclinical Immunology group evaluates the immunogenicity and efficacy of vaccine candidates against viral infectious diseases in suitable animal models. The main focus of the group is to conduct proof of concept studies to generate appropriate scientific data that enable our vaccine candidates to progress towards clinical evaluation and to generate supportive data for clinical trials.
Job Description:
We are seeking a highly motivated senior scientist with at least five years of working experience in the field of vaccines, immunology, or/and virology, preferentially in an industry setting.
The scientist will work on the preclinical evaluation of viral vaccine candidates and participate in cross functional teams to support the development of viral vaccine candidates to clinical testing. The main focus is the support of HIV and/or RSV viral vaccine candidates.
The role requires profound knowledge of immunological techniques such as virus neutralization assays, ELISA, FACS analysis, and other project specific readout systems to characterize the immune response to the vaccine candidates. Thorough knowledge of the immune response in the appropriate animal and in vivo disease models to assess potency and efficacy of vaccine candidates and scientific appreciation of the complexity of immunologic pathways and responses are required.
The scientist will be responsible for the coordination and execution of a research project in order to achieve the goals that are defined for the project. Good skills in documentation, evaluating and reporting results, and writing of protocols for ethical animal experiment approval, scientific documents/papers are required.
The scientist will work in a project team as the preclinical immunological lead. The team is comprised of researchers, clinical developers, analytical development, CMC, and project management. The role requires team player skills, self-motivation and initiative, project management skills, reliability, efficiency, flexibility and enthusiasm.
Areas of responsibility:
• Plan, manage and execute research projects
• Provide scientific rationale for proof of concept and supportive studies
• Keep up to date with newest developments in the field and implement novel technology or readout assays
• Translate research goals into action and accomplish the research target(s)
• Create intellectual property
• Managing of a team to support the vaccine candidate evaluation
• Writing scientific publications and provide input into regulatory documents
Qualifications
Minimum Qualifications:
• PhD
• Art 9 certified (Art 9 is the Dutch equivalent to FELASA C)
• Immunology/Vaccine Background
• Understanding of vaccine manufacturing processes
• Cross functional team thinking
• Scientific skills (knowledge, accuracy, autonomy etc)
• Training and communication skills
• Experience in research project design
Primary Location:Europe/Middle East/Africa-Netherlands-South Holland-Leiden
Organization: Crucell Holland BV (8852)
Job Function: R&D
Description
Crucell is a global biotech company that focuses on the development, production and marketing of vaccines and antibodies to prevent and combat infectious diseases.
Within Crucell talented, entrepreneurial people are working in a dynamic culture in which innovation and a ‘can do’ state of mind are the central points. In order to strengthen our team we are continuously looking for enthusiastic, talented people who have the ambition to develop themselves and can be of value to Crucell.
For our Pre-clinical characterization department, we are looking for a
Senior Scientist Viral Vaccines (m/f)
Department/Project:
The Viral Vaccine department is part of the discovery and early development laboratory and focuses on the research and development of vaccines against viral infectious diseases. Within the Viral Vaccine department, the Preclinical Immunology group evaluates the immunogenicity and efficacy of vaccine candidates against viral infectious diseases in suitable animal models. The main focus of the group is to conduct proof of concept studies to generate appropriate scientific data that enable our vaccine candidates to progress towards clinical evaluation and to generate supportive data for clinical trials.
Job Description:
We are seeking a highly motivated senior scientist with at least five years of working experience in the field of vaccines, immunology, or/and virology, preferentially in an industry setting.
The scientist will work on the preclinical evaluation of viral vaccine candidates and participate in cross functional teams to support the development of viral vaccine candidates to clinical testing. The main focus is the support of HIV and/or RSV viral vaccine candidates.
The role requires profound knowledge of immunological techniques such as virus neutralization assays, ELISA, FACS analysis, and other project specific readout systems to characterize the immune response to the vaccine candidates. Thorough knowledge of the immune response in the appropriate animal and in vivo disease models to assess potency and efficacy of vaccine candidates and scientific appreciation of the complexity of immunologic pathways and responses are required.
The scientist will be responsible for the coordination and execution of a research project in order to achieve the goals that are defined for the project. Good skills in documentation, evaluating and reporting results, and writing of protocols for ethical animal experiment approval, scientific documents/papers are required.
The scientist will work in a project team as the preclinical immunological lead. The team is comprised of researchers, clinical developers, analytical development, CMC, and project management. The role requires team player skills, self-motivation and initiative, project management skills, reliability, efficiency, flexibility and enthusiasm.
Areas of responsibility:
• Plan, manage and execute research projects
• Provide scientific rationale for proof of concept and supportive studies
• Keep up to date with newest developments in the field and implement novel technology or readout assays
• Translate research goals into action and accomplish the research target(s)
• Create intellectual property
• Managing of a team to support the vaccine candidate evaluation
• Writing scientific publications and provide input into regulatory documents
Qualifications
Minimum Qualifications:
• PhD
• Art 9 certified (Art 9 is the Dutch equivalent to FELASA C)
• Immunology/Vaccine Background
• Understanding of vaccine manufacturing processes
• Cross functional team thinking
• Scientific skills (knowledge, accuracy, autonomy etc)
• Training and communication skills
• Experience in research project design
Primary Location:Europe/Middle East/Africa-Netherlands-South Holland-Leiden
Organization: Crucell Holland BV (8852)
Job Function: R&D